Dr Matthew Ryan
MBChB PhD FRCP
Dr Matthew Ryan is a consultant interventional cardiologist at St Thomas’ Hospital and a senior lecturer at King’s College London, with recognised expertise in both general and interventional cardiology. As a general cardiologist at St Thomas’s (rated the UK’s best hospital by Newsweek in 2024) he cares for patients with a wide range of heart conditions, including angina, arrhythmias, heart failure, and syncope, both in outpatient and emergency settings.
His subspecialty is in interventional cardiology, where he performs advanced procedures such as angioplasty and coronary stenting, particularly in complex and high-risk cases referred from across South London and Kent. This includes techniques such as rotational atherectomy, coronary lithotripsy, bifurcation stenting and mechanical circulatory support with both intra-aortic balloon pumps and the Impella device. He is the first author of the “revascularisation for patients with low left ventricular function” chapter of the European Society of Cardiology’s PCI textbook. He also has an interest in coronary physiology, intracoronary imaging and microvascular angina.
Dr Ryan completed his medical degree at the University of Leeds in 2010, graduating with an award for the top performance in finals. After general medical training at UCLH and the Royal Free Hospital, he completed his specialist cardiology training at St Thomas’ Hospital and King’s College Hospital. He was awarded a PhD in Cardiovascular Medicine from King’s College London in 2021.
As a caring and empathetic physician, Dr. Ryan aims to empower his patients through clear communication and tailored treatment plans. He is now offering private consultations for those seeking expert cardiac care in a comfortable and confidential setting.
Research
As a senior lecturer at King’s College London, Dr Ryan is highly active in research. His research focusses on the relationship between coronary artery disease and heart failure, as well as improving the safety of coronary artery stenting in complex or high-risk cases. He has a particular interest in clinical trials.
Dr Ryan has published research in top tier medical journals, including the New England Journal of Medicine, European Heart Journal, Circulation and Journal of the American College of Cardiology. He was a member of faculty for both the European Society of Cardiology and American College of Cardiology Congresses in 2024, presenting the results of major studies at both meetings.
In 2024 Dr Ryan was awarded a prestigious Advanced Fellowship by the National Institute for Health Research and Medical Research Council. The award included £2.8 million to improve our understanding of how coronary artery disease causes heart failure. He is committed to using research to advance patient care and improve the lives of patients with cardiovascular disease.
Recent Scientific Publications
The REVIVED-BCIS2 trial has defined how we treat coronary artery disease in people with heart failure
This international collaboration with colleagues in Yale University, the University of Glasgow and the London School of Hygiene & Tropical Medicine is the first data to inform whether people with heart failure should be treated with stents or heart bypass surgery
This international collaboration with the University of Missouri and London School of Hygiene & Tropical Medicine explored how stenting improves the health of patients with heart failure
Dr Ryan's PhD developed a new way to test heart muscle function during an angiogram
This project advanced our understanding of how coronary microvascular dysfunction develops
This near-completed trial is exploring how to make the most complex stenting procedures safer, by using a temporary pump to support the heart during treatment
Dr Ryan was the lead author of this State-of-the-Art review on treating coronary artery disease in people with heart failure
Affiliations
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King's College London
Senior Clinical Lecturer
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Guy's and St Thomas' NHS Foundation Trust
Consultant Cardiologist
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National Institute for Health Research (UK)
Advanced Fellow
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Royal College of Physicians of Edinburgh
Fellow
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European Society of Cardiology
Member
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British Cardiovascular Intervention Society
Member
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American College of Cardiology
Member
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British Heart Foundation CoRE
Clinical Research Training Fellow